Premature Ovarian Failure (POF)
Premature ovarian failure (POF), also known as primary ovarian insufficiency, is a condition where the ovaries stop functioning normally before age 40. This results in diminished ovarian reserve and reduced fertility.
Some key points about POF:
- Causes can include genetics, autoimmune disorders, infections, chemotherapy/radiation treatments, or unknown reasons.
- Symptoms often include irregular periods, reduced fertility, hot flashes, night sweats, vaginal dryness, and mood changes.
- Diagnosis involves blood tests for hormone levels (FSH, estradiol) and ovarian follicle counts.
- Treatment focuses on managing symptoms and emotional health. Hormone therapy with estrogen/progesterone can help. Infertility treatments may be attempted but success rates are low.
- There is no way to reverse or cure premature ovarian failure. Some residual ovarian function and spontaneous pregnancy is possible in some women.
- Impact on fertility - Egg freezing should be considered for young women diagnosed with POF who want a better chance of having biological children in the future. Using donor eggs is another option.
- Emotional support is important when coping with this life-altering diagnosis. Connecting with others through in-person/online support groups can help.
What are the chances of getting pregnant with POF?
- Spontaneous pregnancy can occasionally happen but chances are low, around 5-10%. Infertility treatments have <35% success rate on average. Using donor eggs boosts IVF success rate to 40-60% per transfer.
What foods or lifestyle changes help with POF?
- Overall health habits to reduce inflammation and autoimmunity may help preserve ovarian function. Eating more antioxidants (berries, tea), omega-3s (fish, walnuts), and probiotic foods can support hormone balance and fertility. Reducing stress through yoga, meditation, acupuncture may also be beneficial.
For more information about Premature Ovarian Failure, visit Harmonize Wellness Clinic.